pentobarbital decreases levels of ponatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Avoid Unless of course the coadministration outweighs the doable risk of ponatinib underexposure; keep track of for signs of diminished efficacy.
pentobarbital will minimize the extent or result of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Strong CYP3A4 inducers may well lessen partiaprevir and ritonavir amounts, and thus decreased efficacy of Viekira Pak
pentobarbital will decrease the extent or influence of solifenacin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lower the level or impact of diclofenac by impacting hepatic enzyme CYP2C9/ten metabolism. Slight/Significance Unidentified.
Keep track of Closely (one)pentobarbital will lessen the extent or impact of linagliptin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Use of different remedies is strongly suggested when linagliptin is to be administered which has a CYP3A4 inducer
pentobarbital will reduce the extent or influence of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. The efficacy of hormonal contraceptives could possibly be lessened. Use of a nonhormonal contraceptive is suggested.
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pentobarbital will reduce the extent or impact of venetoclax by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Contraindicated (1)pentobarbital will lower the extent or outcome of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Females mustn't pick out estradiol valerate/dienogest as their contraceptive while making use of sturdy CYP3A4 inducers as a consequence of potential reduce in contraceptive efficacy.
pentobarbital will lessen the level or impact of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will decrease the extent or effect of mavacamten by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will lower the extent or outcome of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will decrease the extent or result of atorvastatin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an click here eye on.
pentobarbital will lessen the level or outcome of alosetron by impacting hepatic enzyme CYP2C9/ten metabolism. Small/Importance Unknown.